Traffic travelling from Craigavon Bridge is currently being diverted away from Spencer Road after a bus became stuck at the junction of Spencer Road and Fountain Hill.
It is the same junction where lorries have become stuck in recent months.
The PSNI said: "Spencer Road and Fountain Hill remain closed due to a vehicle blocking both Roads and will be for a period of time.
"Please avoid the area and delays should be expected. Thank you for your understanding and patience."
If you have a story or want to send a photo or video to us please contact the Derry Now editorial team on 028 7129 6600 for Derry City stories Or 028 7774 3970 for County Derry stories. Or you can email [email protected] or [email protected] at any time.